Aerobic exercise works best for knee osteoarthritis pain, according to a comprehensive review of 217 clinical trials. Walking, cycling, and swimming reduced pain more effectively than other workout types and improved patients' ability to move freely. The research confirms that exercise is both safe and essential for managing the condition. Strength training and mind-body exercises like yoga provide benefits, but they work best when combined with aerobic activity rather than used alone. This finding matters because knee osteoarthritis affects millions of people worldwide, and many patients seek non-surgical treatment options. The results give doctors and patients clear evidence to guide treatment decisions. Researchers will likely focus next on determining the optimal frequency, duration, and intensity of aerobic exercise for different patient groups. Understanding how exercise timing and progression affect outcomes could help people tailor workouts to their specific needs. The study reinforces that movement, not rest, remains the foundation of effective arthritis management.